We use wide-field and two-photon imaging, multiunit electrophysiology and behavioral experiments, in combination with theoretical approaches, to study how odors are represented at different stages of neural processing. To understand how spatiotemporal neural codes are read by the brain and evoke behavior, we are developing optogenetic pattern stimulation techniques, including 2P holography. Most of the projects are deeply rooted in theoretical approaches and statistical modeling. In addition, as an applied direction, we are developing bio-electronic nose, a universal, versatile, and sensitive chemical detector based on the mouse olfactory system.
